Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.
https://www.stemcell.co.nz/wp-content/themes/osmosis/images/empty/thumbnail.jpg 150 150 NZ Stem Cell Treatment Centre NZ Stem Cell Treatment Centre https://www.stemcell.co.nz/wp-content/themes/osmosis/images/empty/thumbnail.jpgBiochem Pharmacol. 2010 May 15;79(10):1445-54 Authors: Mbalaviele G, Pauley AM, Shaffer AF, Zweifel BS, Mathialagan S, Mnich SJ, Nemirovskiy OV, Carter J, Gierse JK, Wang JL, Vazquez ML, Moore WM, Masferrer JL Inflammation-induced microsomal prostaglandin E synthase-1 (mPGES-1) is the terminal enzyme that synthesizes prostaglandin E(2) (PGE(2)) downstream of cyclooxygenase-2 (COX-2). The efficacy of nonsteroidal…
read more