• After the Covid pandemic, we have resumed stem cell treatments. Appropriate sterility and great care in sanitisation is undertaken as usual. If you are unwell with a cough cold or respiratory symptoms it is best to postpone your procedure.

Novel therapeutic possibilities in systemic lupus erythematosus.

150 150 NZ Stem Cell Treatment Centre

Orv Hetil. 2010 May 2;151(18):735-40.

 

Novel therapeutic possibilities in systemic lupus erythematosus.

[Article in Hungarian]

Bazsó A, Poór G, Gergely P, Kiss E.

Source

Országos Reumatológiai és Fizioterápiás Intézet, Budapest.

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disorder involving different organs and organ systems with consequent characteristic clinical and serologic symptoms. Despite of the improvement in lupus survival, approximately 10-20% of patients do not respond to traditional immune suppressive therapies. Relapses are more frequent; e.g. after cyclophosphamide therapy diffuse proliferative nephritis flares in 1/3 of patients. Different immune competent cells and inflammatory mediators participate in the pathogenesis of SLE involving both the adaptive and innate immunity. Several pathogenic elements and mechanisms may serve as therapeutic targets, consequently. Authors summarize novel therapeutic possibilities and their mechanisms regarding the pathogenesis of SLE. Immune modulation of B and T cells, co-stimulatory pathways, cytokine network, soluble mediators and autologous hemopoietic stem cell transplantation are discussed.

PMID: 20410000 [PubMed – indexed for MEDLINE]