General Orthopedics Library

Repair tissue with human embryonic stem cells and fetal tissues.

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Tissue Eng Part A. 2010 Oct; 16(10) : 3119-37. Repair of full-thickness tendon injury using connective tissue progenitors efficiently derived from human embryonic stem cells and fetal tissues. Cohen S, Leshansky L, Zussman E, Burman M, Srouji S, Livne E, Abramov N, Itskovitz- Eldor J. Sohnis and Forman Families Center for Stem Cell and Tissue…

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Bone marrow and umbilical cord blood human mesenchymal stem cells:

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Int J Clin Exp Med. 2010 Sep 7; 3(4) : 248-69. Bone marrow and umbilical cord blood human mesenchymal stem cells: state of the art. Malgieri A, Kantzari E, Patrizi MP, Gambardella S. Abstract Mesenchymal stem cells (MSCs) are multipotent adult stem cells present in all tissues, as part of the perivascular population. As multipotent…

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Repair of chronic osteochondral defects

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Am J Sports Med. 2010 Sep; 38(9) : 1857-69. Epub 2010 May 27. Repair of chronic osteochondral defects using predifferentiated mesenchymal stem cells in an ovine model. Zscharnack M, Hepp P, Richter R, Aigner T, Schulz R, Somerson J, Josten C, Bader A, Marquass B Abstract BACKGROUND: The use of mesenchymal stem cells (MSCs) to…

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Orthopedics: bone substitutes and beyond.

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Orthopedics. 2010 Sep 7; 33(9) : 661. doi: 10.3928/01477447-20100722-31. Allograft alternatives: bone substitutes and beyond. Goodman SB. Abstract Excessive wear debris, deep infection, periprosthetic fracture, and other causes can lead to bone loss associated with total joint replacements. When performing revisions, surgeons are often preoccupied by the failed implant and the method of replacement, and…

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Cartilage regeneration by bone marrow cells-seeded scaffolds.

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Cartilage regeneration by bone marrow cells-seeded scaffolds. Wegener B, Schrimpf FM, Bergschmidt P, Pietschmann MF, Utzschneider S, Milz S, Jansson V, Müller PE. Abstract Different approaches exist for the treatment of small articular cartilage defects. Several studies show comparable results for autologous chondrocyte implantation (ACI) and microfracture. Unfortunately, the fibrocartilage resulting from microfracture has neither…

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Cell based therapies using adipose tissue-derived cells.

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Stem Cell Res Ther. 2010 Jun 29; 1(2) : 19. Clinical and preclinical translation of cell-based therapies using adipose tissue-derived cells. Gimble JM, Guilak F, Bunnell BA Abstract Adipose tissue is now recognized as an accessible, abundant, and reliable site for the isolation of adult stem cells suitable for tissue engineering and regenerative medicine applications.…

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Augmentation of degenerated human cartilage.

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Arthroscopy. 2009 Dec; 25(12) : 1435-41. Epub 2009 Nov 6. Augmentation of degenerated human cartilage in vitro using magnetically labeled mesenchymal stem cells and an external magnetic device. Kobayashi T, Ochi M, Yanada S, Ishikawa M, Adachi N, Deie M, Arihiro K. Department of Orthopaedic Surgery, Hiroshima University, Hiroshima, Japan. Abstract PURPOSE: The purpose of…

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Cartilage regeneration in osteoarthritis.

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Expert Opin Biol Ther. 2009 Nov; 9(11) : 1399-405. Stem cell therapy for cartilage regeneration in osteoarthritis. Koelling S, Miosge N. Georg August University, Tissue Regeneration Work Group, Department of Prosthodontics, Abteilung Prothetik im Zentrum ZMK, Robert-Koch-Str. 40, Goettingen, D- 37075, Germany. Abstract Enhancing the regeneration potential of hyaline cartilage tissue remains a great challenge.…

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Enhancing chondrogenesis from adipose tissue.

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Tissue Eng Part A. 2009 Jul; 15(7) : 1543-51. Combination of transforming growth factor-beta2 and bone morphogenetic protein 7 enhances chondrogenesis from adipose tissue-derived mesenchymal stem cells. Kim HJ, Im GI Abstract In this study, the authors examined combinations of growth factors that induce effective chondrogenesis from adipose tissue-derived mesenchymal stem cells (MSCs). Human MSCs…

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Quality of newly formed cartilaginous tissue.

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Physiol Res. 2010; 59(4) : 605-14. Epub 2009 Nov 20. Quality of newly formed cartilaginous tissue in defects of articular surface after transplantation of mesenchymal stem cells in a composite scaffold based on collagen I with chitosan micro- and nanofibres. Necas A, Plánka L, Srnec R, Crha M, Hlucilová J, Klíma J, Starý D, Kren…

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