2009 Jun 12; 456(3) : 101-6. Epub 2009 Jan 17. Regeneration and repair in multiple sclerosis: the role of cell transplantation. Pluchino S, Zanotti L, Brini E, Ferrari S, Martino G. Neuroimmunology Unit and Institute of Experimental Neurology (INSpe), DIBIT-San Raffaele Scientific Institute, via Olgettina 58, 20123 Milano, Italy. Abstract Physiological (spontaneous) and reactive (reparative)…

2009 Jun;5(6):300-2 Multiple sclerosis: Hematopoietic stem cell transplantation: hope and hype. Stangel M Abstract A trial of autologous hematopoietic stem cell transplantation to treat multiple sclerosis has yielded promising results, generating considerable interest within both the clinical literature and the mainstream press.the findings should, however, be interpreted with some caution, and larger, randomized trials will…

2009; 7:29 Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis. Riordan NH, Ichim TE, Min WP, Wang H, Solano F, Lara F, Alfaro M, Rodriguez JP, Harman RJ, Patel AN, Murphy MP, Lee RR, Minev B Abstract The stromal vascular fraction (SVF) of adipose tissue is known to contain mesenchymal stem cells (MSC),…

2008 Dec; 2(4) : 699-705 Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies. Greco SJ, Rameshwar P Abstract The therapeutic utilization of stem cells has been ongoing for several decades, principally in the form of bone marrow (BM) transplants to treat various hematological disorders and other immune-related diseases. More recently,…

2008 Nov; 110(9) : 889-96. Epub 2008 Mar 28. The potential use of stem cells in multiple sclerosis: an overview of the preclinical experience. Karussis D, Kassis I. Department of Neurology, Laboratory of Neuroimmunology, Agnes-Ginges Center for Neurogenetics, Hadassah-Hebrew University Hospital, Ein-Karem, Jerusalem, Israel. karus@cc.huji.ac.il Abstract The reported neurodegeneration process in multiple sclerosis may explain…

2004 Sep; 24(3) : 159-71. Human neural stem cells genetically modified for brain repair in neurological disorders. Kim SU. Brain Disease Research Center, Ajou University School of Medicine, Suwon, Korea. sukim@ajou.ac.kr Abstract Existence of multipotent neural stem cells (NSC) has been known in developing or adult mammalian CNS, including humans. NSC have the capacity to…